Skip to Main Content

Evidence-Based Medicine (EBM) Resources: Home

The Evidence Pyramid

The Evidence Pyramic

Filtered Resources

  • Evaluate how recently the summary was updated or revised
  • Not all topics are covered by filtered information resources 
  • If your topic is not covered you’ll need to search the primary or unfiltered literature.   
  • Resources for Systematic Reviews, Meta-Analyses: Cochrane Database of Systematic Reviews, MEDLINE/PubMed  (Meta-Analysis or Systematic Reviews types, or Clinical Queries, Systematic Reviews)
  • Resources for Evidence Summaries and Evidence Guidelines: MEDLINE/PubMed (Practice Guideline types), Embase

Unfiltered Resources

  • Better known as “primary literature” 
  • It is up to YOU to assess quality, validity and applicability to your patient 
  • Searching Unfiltered Resources, requires more time and expertise 
  • Resources for Randomized Controlled Trials: MEDLINE/PubMed (Randomized Controlled Trial type), Embase  

Background Resources

  • To learn about a new topic or refresh knowledge
  • To provide a comprehensive overview of a disease, condition or concept
  • Usually in textbook form, but can be online
  • Resources for Background Information, Expert Opinion: Textbooks/eBooks, UpToDate 

EBM Steps

  1. Ask: Define your clinical question(s). Start with a clinical problem or question arising from the care of the patient. Use the PICOTT formula to create a good question.
  2. Acquire: Search for the research evidence that addresses your question(s).
  3. Appraise: Evaluate and assess the validity, creditability, and applicability of the evidence.
  4. Apply: Apply the evidence in practice. Incorporate valid evidence with patient values and preferences, clinical context, and health system issues; implement the decision in practice. 

What is EBM?

Evidence-based medicine (EBM) is the integration of best research evidence with clinical expertise and patient values.

  • by best research evidence we mean clinically relevant research, often from the basic sciences of medicine, but especially from patient centered clinical research into the accuracy and precision of diagnostic tests (including the clinical examination), the power of prognostic markers, and the efficacy and safety of therapeutic, rehabilitative, and preventive regimens. New evidence from clinical research both invalidates previously accepted diagnostic tests and treatments and replaces them with new ones that are more powerful, more accurate, more efficacious, and safer.
  • by clinical expertise we mean the ability to use our clinical skills and past experience to rapidly identify each patient's unique health state and diagnosis, their individual risks and benefits of potential interventions, and their personal values and expectations.
  • by patient values we mean the unique preferences, concerns and expectations each patient brings to a clinical encounter and which must be integrated into clinical decisions if they are to serve the patient.

When these three elements are integrated, clinicians and patients form a diagnostic and therapeutic alliance which optimizes clinical outcomes and quality of life.

From: Knowledge Translation Program